Alterations of the insulin-like growth factor system in patients with polycythemia vera
โ Scribed by P. Michl; G. Spoettl; D. Engelhardt; M.M. Weber
- Book ID
- 117462755
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 253 KB
- Volume
- 181
- Category
- Article
- ISSN
- 0303-7207
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The insulin-like growth factor (IGF) system is involved in the regulation of cell growth. The system involves a network of molecules that includes the IGFs themselves (IGF-I and -II), IGF receptors (types I and II), IGF-binding proteins (IGFBP-1 through -6), and IGFBP proteases. Characterization of
## Abstract Insulinโlike growth factors (IGFs) play an important role in cell growth and differentiation, and the liver is the main source of IGFs and IGFโbinding proteins (IGFBPs) that appear in the circulation. The effect of liver cysts on the circulating IGF system was studied in this work. Seru