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Genetic alterations in colorectal cancers with demethylation of insulin-like growth factor II

✍ Scribed by Miki Ohta; Takafumi Sugimoto; Motoko Seto; Dai Mohri; Yoshinari Asaoka; Motohisa Tada; Yasuo Tanaka; Yutaka Yamaji; Fumihiko Kanai; Takao Kawabe; Masao Omata

Book ID
116534516
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
538 KB
Volume
39
Category
Article
ISSN
1532-8392

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## Abstract Loss of imprinting (LOI), the biallelic expression of an imprinting gene, of insulin‐like growth factor 2 (__IGF2__) has been reported to be associated with colorectal carcinogenesis because of its high prevalence in normal colorectal mucosa as well as cancerous tissue in patients with