## Abstract We demonstrate in cell culture that mammary epithelial cells from normal human breast specimens metabolize benzo(a)pyrene (BaP) and form adducts with the bases of their DNA more readily and at lower concentrations of BaP than do fibroblasts from the same specimens. BaP metabolism and ad
Alterations of pulmonary benzo[a]pyrene metabolism by reactive oxygen metabolites
β Scribed by N. Lynn Flowers; Philip R. Miles
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 965 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0300-483X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A modified fluorometric procedure for the determination of basal aryl hydrocarbon hydroxylase activity in human hair follicles is described. The method is also applicable for measurement of induction of the enzyme in primary cultures of keratinocytes originating from hair follicles. For good sensiti
## Abstract A rat liver microsomeβmediated bacterial mutagenicity test showed 9βhydroxybenzo (__a__) pyrene to be significantly more effective as a preβmutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex