The metabolic activation of benzo(a)pyre
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Ronald A. Lubet; Jorge Capdevila; Russell A. Prouoh
📂
Article
📅
1979
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John Wiley and Sons
🌐
French
⚖ 473 KB
👁 1 views
## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex