𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Alterations of PTEN/MMAC1, a candidate tumor suppressor gene, and its homologue, PTH2, in small cell lung cancer cell lines

✍ Scribed by Kim, Se K; Su, Li-Kuo; Oh, Yun; Kemp, Bonnie L; Hong, Waun K; Mao, Li


Book ID
110061081
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
371 KB
Volume
16
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Oncogene expression in small-cell lung c
✍ Kalle Saksela; Tomi P. MΓ€kelΓ€; Kari Alitalo πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 French βš– 894 KB

N-myc and L-myc proto-oncogenes are expressed in many developing embryonic tissues. In contrast to expression of the closely related c-myc gene, N-myc and L-myc expression is very restricted in adult tissues. We show that small amounts of the L-myc RNA can be detected in normal adult testicular tiss

Hypermethylation of RASSF1A and BLU tumo
✍ Carmen J. Marsit; Duk-Hwan Kim; Mei Liu; Philip W. Hinds; John K. Wiencke; Heath πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 82 KB πŸ‘ 1 views

## Abstract The putative tumor suppressors __RASSF1A__ and __BLU__ are mapped adjacent to one another on chromosome 3p21.3, a region frequently deleted in lung cancer. These genes are often inactivated by promoter hypermethylation, but the association of this inactivation with clinical features of

Molecular characterization of a large ho
✍ Farida Latif; Kalman Tory; William S. Modi; Stephen L. Graziano; Gary Gamble; Je πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 844 KB

## Abstract Homozygous deletions are instrumental in the detection and cloning of tumor suppressor genes. We report the isolation and characterization of 39 new single‐copy probes saturating a submicroscopic homozygous deletion detected in the DNA of the small cell lung cancer (SCLC) cell line U202