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Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers

✍ Scribed by Chin-San Liu; Haw-Wen Chen; Chong-Kuei Lii; Ching-Shan Tsai; Chen-Ling Kuo; Yau-Huei Wei

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
87 KB
Volume
40
Category
Article
ISSN
0893-6692

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Mutations occur in mitochondrial DNA (mtDNA) in a strand-asymmetric manner. The suppressed usage of cysteine residues in the H-strandencoded subunits can be ascribed to the mutational instability of the codon for cysteine. The usage of cysteine was suppressed even in the L-strand-encoded ND6 subunit