A New Zealand and a Scottish pedigree with maternally inherited sensorineural deafness were both previously shown to carry a heteroplasmic A7445G mutation in the mitochondrial genome. More detailed clinical examination of the New Zealand family showed that the hearing loss was progressive, with the
Cosegregation of the mitochondrial DNA A1555G and G4309A mutations results in deafness and mitochondrial myopathy
✍ Scribed by Y. Campos; A. García; A. López; S. Jiménez; J.C. Rubio; P. Del Hoyo; F. Bustos; M.A. Martín; A. Cabello; J.R. Ricoy; J. Arenas
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 230 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0148-639X
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## Abstract ## Objective We studied the prevalence, segregation, and phenotype of the mitochondrial DNA 3243A>G mutation in children in a defined population in Northern Ostrobothnia, Finland. ## Methods Children with diagnoses commonly associated with mitochondrial diseases were ascertained. Blo
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