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Alterations of both responder T cells and stimulator non-T cells are responsible for abnormal mixed lymphocyte reaction in aged humans

✍ Scribed by Maria Grazia Giudizi; Fabio Almerigogna; Roberta Biagiotti; Anna Alessi; Paola Paoli; Carlo Colonna; Sergio Romagnani


Book ID
105651084
Publisher
Springer
Year
1984
Tongue
English
Weight
386 KB
Volume
14
Category
Article
ISSN
0940-5437

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It is now well recognized that a large proportion of cases with acute lymphoblastic leukemia are classified as non-T/non-B neoplastic disease. The origin of leukemic non-Thon-B cells is at present not known. It has been shown that fresh or cultured leukemic T lymphoblasts exert no stimulating capaci