Alterations in the morphology of rat liver cells influenced by insulin
โ Scribed by Morgan, Carl R. ;Jersild, Ralph A.
- Publisher
- John Wiley and Sons
- Year
- 1970
- Tongue
- English
- Weight
- 998 KB
- Volume
- 166
- Category
- Article
- ISSN
- 0003-276X
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Abbreviations: IGF II, insulin-like growth factor II; IGF1R, type 1 insulin-like growth in which oval cell lines established from the livers of unfactor receptor; M6P/IGF2R, type 2 insulin-like growth factor receptor; FBS, fetal bovine treated 36 or carcinogen-treated rats [40] have been transserum;
Injection of pig serum into rats twice a week for 8 weeks induced stellate cell activation resulting in liver fibrosis without parenchymal cell injury. Administration of a choline deficient L-amino acid defined (CDAA) diet for 6 weeks with or without pig serum pretreatment led to the development of