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Alterations in telomeric repeat length in lung cancer are associated with loss of heterozygosity in p53 and Rb

Book ID: 123217138
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 134 KB
Volume: 13
Category: Article
ISSN: 0169-5002
DOI: 10.1016/0169-5002(95)90558-8

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## Abstract RB protein expression and loss of heterozygosity (LOH) in the RB gene were studied in 77 primary lung carcinomas of all histological types. RB protein expression was studied by immunohistochemistry with 3 anti‐RB antibodies, and was found altered in 23/29 (79%) neuro‐endocrine (NE) carc