Alterations in Sympathetic Noradrenergic Innervation in Lymphoid Organs with Age
โ Scribed by KELLEY S. MADDEN; S. THYAGARAJAN; DAVID L. FELTEN
- Book ID
- 111393930
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 564 KB
- Volume
- 840
- Category
- Article
- ISSN
- 0890-6564
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๐ SIMILAR VOLUMES
Noradrenergic postganglionic sympathetic innervation of the spleen in 8-month-old (adult) and 27-monthold (aged) Fischer 344 (F344) rats was examined using fluorescence histochemistry for catecholamines coupled with stereologic point-counting analysis for quantitation of noradrenergic varicosities.
Age-associated changes in the immune system are responsible for an increased likelihood of infection, autoimmune diseases, and cancer in the elderly. Immunosenescence is characterized by reduced levels of the peripheral naive T cell pool derived from thymus and the loss of immature B lineage cells i