Alterations in sympathetic innervation of thymus and spleen in aged mice
โ Scribed by Kelley S Madden; Denise L Bellinger; Suzanne Y Felten; Eric Snyder; Mary E Maida; David L Felten
- Book ID
- 119484867
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 538 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0047-6374
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The ontogeny of noradrenergic innervation and its compartmental development were studied in the rat spleen using glyoxylic acid histofluorescence and highperformance liquid chromatography (HPLC). Noradrenergic nerves were present at birth in bundles adjacent to the splenic artery and vein. On days 1
Noradrenergic postganglionic sympathetic innervation of the spleen in 8-month-old (adult) and 27-monthold (aged) Fischer 344 (F344) rats was examined using fluorescence histochemistry for catecholamines coupled with stereologic point-counting analysis for quantitation of noradrenergic varicosities.