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Alterations in plasma sialyltransferase levels in patients with neoplastic disease

โœ Scribed by Michael Henderson; David Kessel

Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
460 KB
Volume
39
Category
Article
ISSN
0008-543X

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โœฆ Synopsis

Levels of g1ycoprotein:sialyltransferase activity (EC 2.4.99.1 ; CMP-acetylneuraminate:D-galactosyl-glycoprotein N-acetylneuraminyl-transferase) were measured in plasma of patients with neoplastic disease, and were found elevated above normal control values in 85% of patients examined. There was a correlation between enzyme levels and course of disease in 46 of 57 patients studied serially during therapy. Plasma sialyltransferase may be a useful marker enzyme for monitoring effectiveness of therapeutic programs for disseminated neoplasms.

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