Alterations in neutral amino acid transport across the blood-brain barrier in hepatic failure
β Scribed by A. Watanabe; T. Higashi; T. Shiota; N. Takei; T. Sakata; M. Fujiwara; H. Nakatsukasa; M. Kobayashi; H. Nagashima
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 579 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0372-8722
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We repeatedly measured blood-brain barrier passage of phenylalanine, leucine, glucose and GABA in nine patients with hepatic encephalopathy using the intravenous double-indicator technique. Controls were four patients without liver disease and two of the patients who had recovered completely from th
## Abstract The permeability of the blood brain barrier (BBB) to Ξ²βhydroxybutyrate (Ξ²βHB) was computed in fed and starved (five days) rats by the simultaneous measurement of cerebral blood flow (diffusible indicator methodβ^123^Iβiodoantipyrine) and brain uptake of ^14^CβΞ²βHB (relative to a ^3^H~2~