Transport of amino acids across the blood-brain barrier: Implications for treatment of maternal phenylketonuria
โ Scribed by R. M. Gardiner
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 556 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0141-8955
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We repeatedly measured blood-brain barrier passage of phenylalanine, leucine, glucose and GABA in nine patients with hepatic encephalopathy using the intravenous double-indicator technique. Controls were four patients without liver disease and two of the patients who had recovered completely from th
The blood-brain barrier (BBB) is formed by the presence of tight junction complexes between brain endothelial cells that restrict paracellular permeability. As a consequence, a number of transport proteins are expressed on cerebral endothelial cells to facilitate the transport of nutrients into the