𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat

✍ Scribed by Igor P. Pogribny; Barbara J. Miller; S.Jill James


Book ID
117468919
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
773 KB
Volume
115
Category
Article
ISSN
0304-3835

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Alterations in the Ha-ras-1 and the p53
✍ Katherine E. McKenzie; Barbara A. Armstrong; Ying Chen; Mahalakshmi Nagarajan; C πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 217 KB πŸ‘ 2 views

Well-differentiated mammary carcinomas carrying mutated Ha-ras-1 oncogenes arise frequently in pubescent rats exposed to the direct-acting methylating agent N-methyl-N-nitrosourea (MNU). When these tumors are serially transplanted, they acquire more aggressive phenotypes. To determine the genetic al

Expression of the p16INK4a gene and meth
✍ Kanya Honoki; Toshifumi Tsujiuchi; Toshio Mori; Kazuhiro Yoshitani; Masahiro Tsu πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 112 KB

## Abstract Loss of p16^INK4a^ protein expression has frequently been related to DNA methylation in association with gene silencing. Although the methylation status of exon1Ξ± for p16^INK4a^ involvement in various cancers has been extensively analyzed, it has been pointed out that some inconsistenci

No consistent pattern of mutations in p5
✍ Hannu Komulainen; Pasi Hakulinen; Kristina Servomaa; Kaisa Makkonen; Ritva Vasar πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 78 KB πŸ‘ 2 views

The frequency of point mutations in p53 (exons 4 -7) and in Ki-ras, Ha-ras, and N-ras (exons 1 and 2) and the expression of p53 protein were evaluated in the liver tumors of Wistar rats of a 104week carcinogenicity study on 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a chlorine disinf