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Alteration of peripheral blood lymphocytes profile with HBsAg level in chronic hepatitis B infection

✍ Scribed by Hadi, Q.N.; Mustafa, M.I.A.-D.; Yee, C.H.; Jaafar, K.A.


Book ID
124128411
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
63 KB
Volume
21
Category
Article
ISSN
1201-9712

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In Vitro Response to HBsAg of Peripheral
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Lymphocytes isolated from recipients of hepatitis B vaccine were studied for their immune response to HBsAg in uitro. Peripheral blood mononuclear cells (PBMs) from 70 to 80% of 40 vaccinees yielded proliferative indices larger than 2 after 5 to 7 days incubation with HBsAg. This in uitro proliferat

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Spontaneous loss of HBsAg is infrequent in adult HBV carriers. Little is known about this serological change in children. In a prospective study of 420 hepatitis B virus-carrier children who were observed for 1 to 12 yr (mean = 4.3 yr), spontaneous loss of HBsAg occurred in 10 patients, with an aver