Altered expression of cyclin D1 and CDK4
β
Valeria Masciullo; Giovanni Scambia; Maria Marone; Cecilia Giannitelli; Gabriell
π
Article
π
1997
π
John Wiley and Sons
π
French
β 130 KB
π 2 views
We analyzed the expression and amplification of cyclin D1 and CDK4 genes in ovarian carcinomas. Northern blot analysis revealed overexpression of cyclin D1 in 12 of 65 (18%) ovarian carcinomas while CDK4 was overexpressed in 7 of 48 cases (14%). None of the tumors showed amplification of any of the