Alteration of cell growth and morphology by overexpression of transforming growth factor β type II receptor in human lung adenocarcinoma cells
✍ Scribed by Kim, Tae-Kyun; Mo, Eun Kyung; Yoo, Chul-Gyu; Lee, Choon-Taek; Han, Sung Koo; Shim, Young-Soo; Kim, Young Whan
- Book ID
- 118569463
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 604 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0169-5002
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
To analyze transforming growth factor-b (TGF-b) response during MCF-7 cell progression, early passage (MCF-7E, õ200 passage) and late passage (MCF-7L, ú 500 passage) cells were compared. MCF-7E cells showed an IC 50 of Ç10 ng/ ml of TGF-b1, whereas MCF-7L cells were insensitive. MCF-7E cells contain
Retinoblastoma cells are resistant to transforming growth factor-b (TGF-b) activity due to the absence of TGF-b binding. To further elucidate the mechanism of TGF-b resistance, we studied the expression of the TGF-b receptors and SMADs by using the Y79 and WERI-Rb-1 retinoblastoma cell lines. Bindin