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Alpha7 nicotinic acetylcholine receptor: A link between inflammation and neurodegeneration

✍ Scribed by Concepcion Conejero-Goldberg; Peter Davies; Luis Ulloa


Book ID
103853422
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
307 KB
Volume
32
Category
Article
ISSN
0149-7634

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Alpha7 nicotinic acetylcholine receptor
✍ Giovanni Grazioso; Andrea Cavalli; Marco De Amici; Maurizio Recanatini; Carlo De πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 479 KB

## Abstract A group of agonists for the Ξ±7 neuronal nicotinic acetylcholine receptors (nAChRs) was investigated, and their free energies of binding Ξ”__G__~bind~ were calculated by applying the molecular mechanics Poisson–Boltzmann surface area (MM‐PBSA) approach. This method, based on molecular dyn