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Alpha7 Nicotinic Acetylcholine Receptor Expression and Activity During Neuronal Differentiation of PC12 Pheochromocytoma Cells

✍ Scribed by Arthur A. Nery; Rodrigo R. Resende; Antonio H. Martins; Cleber A. Trujillo; Vesna A. Eterovic; Henning Ulrich


Book ID
107575320
Publisher
Humana Press Inc
Year
2010
Tongue
English
Weight
657 KB
Volume
41
Category
Article
ISSN
0895-8696

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## Abstract The mechanism for a large loss of neuronal nicotinic acetylcholine receptors (nAChRs) in brains with neurodegenerative diseases remains unclear. Based on our previous results of [^3^H]epibatidine binding influenced by lipid peroxidation, we suggest that nAChR deficit in neurodegenerativ