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Alpha1-acid glycoprotein concentration and serum protein binding of carbamazepine and carbamazepine-10,11 epoxide in children with epilepsy

✍ Scribed by M. Contin; R. Riva; F. Albani; E. Perucca; G. Lamontanara; A. Baruzzi

Publisher
Springer
Year
1985
Tongue
English
Weight
422 KB
Volume
29
Category
Article
ISSN
0031-6970

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In vivobinding characteristics of carbam
In vivobinding characteristics of carbamazepine and carbamazepine-10, 11-epoxide to serum proteins in paediatric patients with epilepsy
✍ Y. Kodama; K. Tsutsumi; M. Kuranari; H. Kodama; I. Fujii; M. Takeyama πŸ“‚ Article πŸ“… 1993 πŸ› Springer 🌐 English βš– 292 KB

The in vivo serum protein binding characteristics of carbamazepine (CBZ) and carbamazepine-10,11-epoxide (CBZ-E) were assessed in sera from 23 paediatric patients on CBZ monotherapy. We assumed that CBZ and CBZ-E binding to serum proteins comprised specific binding sites on alpha 1-acid glycoprotein