We analyzed serum triglyceride (TG) levels in 22 chronic myeloid leukemia (CML) patients treated with interferon-a (IFN-a). Hypertriglyceridemia was present in one-half of patients at diagnosis, and IFN-a treatment was associated with a further increase in 90% of the total group of patients. This in
ALPHA-INTERFERON AND PREGNANCY IN A PATIENT WITH CML
β Scribed by J. H. LIPTON; C. M. DERZKO; J. CURTIS
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 268 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0278-0232
No coin nor oath required. For personal study only.
β¦ Synopsis
A 34-year-old woman on interferon for CML for 7 years, experienced problems with conception. Full work-up revealed a short luteal phase and therapy with clomiphene was initiated. Pregnancy occurred and a normal infant was delivered by C-section. The detailed infertility evaluation is described and the impact of interferon therapy on pregnancy is reviewed. Successful pregnancy appears possible in woman taking interferon on a chronic basis.
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Background. Prolonged therapy with interferon (IFN) may lead to the formation of IFN antibodies. Methods. Patients with renal cell carcinoma (n = 270) with advanced localized disease were randomized after complete tumor resection to receive treatment with adjuvant recombinant IFN-alpha-2a (rIFN-a2a
## Abstract The effect of Ξ±βinterferon on the hepatitis C genotypes was examined in 25 antiβHCVβpositive hemophilic patients. The rate of multiple HCV genotypes in patients who are likely to have mixed infections was also studied. Pretreatment results showed that 3/25 (12%) patients had a change in