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Hypertriglyceridemia may be severe in CML patients treated with interferon-α

✍ Scribed by María Jesús Peñarrubia; Dr. Juan Luis Steegmann; Esperanza Lavilla; Felipe Casado; María José Requena; Mónica Picó; Reyes Arranz; José María Fernández-Rañada

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
188 KB
Volume
49
Category
Article
ISSN
0361-8609

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✦ Synopsis

We analyzed serum triglyceride (TG) levels in 22 chronic myeloid leukemia (CML) patients treated with interferon-a (IFN-a). Hypertriglyceridemia was present in one-half of patients at diagnosis, and IFN-a treatment was associated with a further increase in 90% of the total group of patients. This increase was maximal during the first months of therapy. Four patients (18%) reached levels higher than 1,000 mg/dl. This is the first report describing this secondary effect in CML patients treated with IFN-a.

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