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Alpha cell function in health and disease: influence of glucagon-like peptide-1

✍ Scribed by B. E. Dunning; J. E. Foley; B. Ahrén


Publisher
Springer
Year
2005
Tongue
English
Weight
220 KB
Volume
48
Category
Article
ISSN
0012-186X

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## Abstract In an attempt to develop a high producing mammalian cell line expressing CNTO736, a Glucagon like peptide‐1‐antibody fusion protein (also known as a Glucagon like peptide‐1 MIMETIBODY^TM^), we have noted that the N‐terminal GLP‐1 portion of the MIMETIBODY^TM^ was susceptible to proteoly