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Alpha-1 Antitrypsin Deficiency: Pathogenesis, Clinical Presentation, Diagnosis, and Treatment

✍ Scribed by Thomas Köhnlein; Tobias Welte

Book ID
116211729
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
953 KB
Volume
121
Category
Article
ISSN
1555-7162

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In recent years, we have witnessed several important paradigm shifts in understanding the molecular basis of liver disease in alpha-1-antitrypsin (AT) deficiency. These shifts have become possible as a result of a number of advances in research on the cell biology of aggregation-prone mutant protein