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Outcome of PiSS and PiSZ alpha-1-antitrypsin deficiency presenting with liver involvement

✍ Scribed by Nedim Hadzic; Ruggiero Francavilla; Susan M. Chambers; Stefania Castellaneta; Bernard Portmann; Giorgina Mieli-Vergani


Publisher
Springer
Year
2005
Tongue
English
Weight
195 KB
Volume
164
Category
Article
ISSN
0340-6997

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Molecular pathogenesis of alpha-1-antitr
✍ David H. Perlmutter; Jeffrey L. Brodsky; William F. Balistreri; Bruce C. Trapnel πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 321 KB

In recent years, we have witnessed several important paradigm shifts in understanding the molecular basis of liver disease in alpha-1-antitrypsin (AT) deficiency. These shifts have become possible as a result of a number of advances in research on the cell biology of aggregation-prone mutant protein