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Alpha-1-antichymotrypsin bi-allele polymorphism, apolipoprotein-E tri-allele polymorphism and genetic risk of Alzheimer's syndrome

✍ Scribed by J. Thome; A. Baumer; J. Kornhuber; M. Rösler; P. Riederer

Book ID
105513620
Publisher
Springer
Year
1995
Tongue
English
Weight
382 KB
Volume
10
Category
Article
ISSN
1435-1463

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A common polymorphism in the α1-antichymotrypsin (ACT) gene has been found to modify the APOE\*4-associated risk of Alzheimer's disease due to an apparent interaction between the two loci. This study was undertaken to determine the gender-and age-related distributions of these two polymorphisms in t