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Allylamine cardiovascular toxicity: V. tissue distribution and toxicokinetics after oral administration

โœ Scribed by Paul J. Boor

Book ID
103655590
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
545 KB
Volume
35
Category
Article
ISSN
0300-483X

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## Abstract The subacute toxicities (10 male and 10 female rats at each dose) and the toxicokinetics (5 male rats at each dose) of DAโ€8159, a new phosphodiesterase type V (PDE V) inhibitor, were evaluated after single (at day 1) and 4โ€week (at day 28) oral administration of the drug at doses of 0 (