Toxicokinetics of bisphenol A in female DA/Han rats after a single i.v. and oral administration
β Scribed by Andreas Upmeier; Gisela H. Degen; Patrick Diel; Horst Michna; Hermann M. Bolt
- Publisher
- Springer-Verlag
- Year
- 2000
- Tongue
- English
- Weight
- 124 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0340-5761
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## Abstract The subacute toxicities (10 male and 10 female rats at each dose) and the toxicokinetics (5 male rats at each dose) of DAβ8159, a new phosphodiesterase type V (PDE V) inhibitor, were evaluated after single (at day 1) and 4βweek (at day 28) oral administration of the drug at doses of 0 (
The subacute toxicities and toxicokinetics of a new erectogenic, DA-8159, were evaluated after single (at the 1st day) and 4-week (at the 28th day) oral administration of the drug, in doses of 0 (to serve as a control), 12.5, 50 and 200 mg/kg/day, to male and female dogs (n ΒΌ 3 for male and female d