A Photochemical Switch for Controlling P
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Sonia K. Pollitt; Peter G. Schultz
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Article
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1998
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John Wiley and Sons
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English
β 113 KB
π 3 views
Incorporation of an unnatural amino acid containing a photolabile group in the side chain allows specific interactions between two proteins to be prevented. The photocaged ras protein in which Aspβ38 has been substituted by its Ξ²-nitrobenzyl ester (Nb) is unable to interact with its effector protein