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Allosteric interaction on muscarinic receptors: Facts, theory and fantasies

✍ Scribed by J. Prošska

Book ID
117175442
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
83 KB
Volume
60
Category
Article
ISSN
0024-3205

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Allosteric binding sites on muscarinic receptors
✍ John Ellis 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB

The classical (acetylcholine) binding sites of all five subtypes of muscarinic receptors are known to be subject to allosteric regulation by a variety of small molecules. The hallmarks of such modulation in binding assays are that the allosteric ligands can alter both the affinities and the rates of