Neonatal alloimmune thrombocytopenia is an uncommon but important cause of thrombocytopenia in infants. Because of the severity of the thrombocytopenia, some of these infants will have intracranial hemorrhage with resultant long-term disability. Obstetricians and neonatologists have recommended deli
Alloimmune neonatal thrombocytopenia associated with incidental maternal thrombocytopenia
โ Scribed by Robert F. Burrows; John G. Kelton
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 188 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0361-8609
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๐ SIMILAR VOLUMES
We report two patients where the finding of isolated fetal hydrocephalus led to the detection of severe fetal thrombocytopenia, using fetal blood sampling. Serological investigation led to the diagnosis of fetomaternal alloimmune thrombocytopenia (FMAIT) due to anti-HPA-I a. Both women had had previ
## 359 indomethacin treatment (26.0 5 15.6%; P < 0.005). When PBL were obtained from the patient during periods of medication or from the healthy control, in vitro addition of indomethacin did not cause a significant change in generation of Con A-SC. These data showing that the reduced generation