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Allergy in systemic lupus erythematosus. IgE levels and reaginic phenomenon

✍ Scribed by John A. Goldman; Grace Ann Klimek; Rida Ali

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
553 KB
Volume
19
Category
Article
ISSN
0004-3591

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✦ Synopsis

Twenty-seven patients with systemic lupus erythematosus (SLE) were investigated for the presence of allergic reactivity, and serum IgE levels were measured by immunoassay. Compared to controls, SLE patients had significant increases of only allergic rhinitis and drug allergy. Despite the usual hyperimmunoglobulinemia in SLE, IgE levels were not elevated (mean: 251 IU). Because recent reports have noted elevated IgE in rheumatoid arthritis, this finding may suggest basic immunologic differences between rheumatoid arthritis and SLE.

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