𝔖 Bobbio Scriptorium
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Salivary testosterone levels in women with systemic lupus erythematosus

✍ Scribed by Miguel A. Navarro; Antonio Vidaller; Juan B. Ortolá; Maria R. Bonnin; Maria V. Pac; Isabel Moga

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
197 KB
Volume
35
Category
Article
ISSN
0004-3591

No coin nor oath required. For personal study only.

✦ Synopsis

Objective. To measure salivary testosterone in women with systemic lupus erythematosus (SLE).

Methods. We investigated concentrations of salivary testosterone in 13 women with active SLE and 47 women with inactive SLE, and in 72 healthy female controls.

Results. We found a significant decrease in salivary testosterone concentrations in glucocorticoidtreated SLE patients (mean 2 SD 0.06 f 0.04 nmoled liter) but no differences in concentrations in untreated patients (0.09 f 0.03 nmolesfiiter), compared with the healthy controls (0.11 f 0.04 nmoleshiter).

Conclusion. Glucocorticoid treatment appears to cause a decrease in the salivary testosterone level. Measurement of salivary testosterone is a simple way of monitoring androgen metabolism in patients with SLE.

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