Allergic contact dermatitis to ultraviolet (UV) cured acrylates occurs predominantly in occupationally exposed workers. Two men presented with dermatitis coinciding with the location of banknotes in their pockets. Patch testing confirmed allergic contact dermatitis to multiple acrylates and Australi
Allergic contact dermatitis to various salols (phenyl salicylates)
β Scribed by Bernard Marchand; Pierre Barbier; Georges Ducombs; Jean Foussereau; Pierre Martin; Claude Benezra
- Publisher
- Springer-Verlag
- Year
- 1981
- Tongue
- English
- Weight
- 326 KB
- Volume
- 272
- Category
- Article
- ISSN
- 0340-3696
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β¦ Synopsis
Patients sensitive to phenyl salicylate (salol) were patch-tested to several aryl salicylates. The most powerful derivative was p-nitrophenyl salicylate (compound 5). This can be explained by an unusually good interaction with protein (nucleophilic substitution on the carboxyl carbon). All these results were confirmed by experimental sensitization of guinea pigs to salol and crossreaction to substituted salols. The results are in line with current theory of allergic contact dermatitis, i.e., an in vivo formation of a hapten-protein conjugate.
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