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Allelic variation of a functional polymorphism in the serotonin transporter gene and depression in Parkinson's disease

✍ Scribed by David J. Burn; Watcharee Tiangyou; Liesl M. Allcock; Jill Davison; Patrick F. Chinnery

Book ID: 116820142
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 73 KB
Volume: 12
Category: Article
ISSN: 1353-8020
DOI: 10.1016/j.parkreldis.2005.11.005

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## Abstract Altered levels of the neurotransmitters dopamine and serotonin are observed in both Parkinson's disease (PD) and depression. Therefore, the neurotransmitter transporter genes, __SLC6A3__ (dopamine) and __SLC6A4__ (serotonin) are candidates for depression in PD. We genotyped 24 tagging S