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Allelic polymorphisms and RFLP in the human immunoglobulin lambda light chain locus

✍ Scribed by Marie-Paule Lefranc; Nathalie Pallarès; Jean-Pol Frippiat

Book ID
106137167
Publisher
Springer
Year
1999
Tongue
English
Weight
160 KB
Volume
104
Category
Article
ISSN
0340-6717

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During the initial stages of B lymphocyte differentiation heavy chain variable (VH), diversity (DH) and joining (JH) gene segments recombine to form a functional heavy chain variable region (VDJ) gene. Evidence for genetic polymorphism of the human JH gene segments has been obtained from mature rear