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Allelic loss on chromosomes 2q, 3p and 21q: possibly a poor prognostic factor in oral squamous cell carcinoma

โœ Scribed by Nobuharu Yamamoto; Jun-etsu Mizoe; Hideyuki Numasawa; Hirohiko Tsujii; Takahiko Shibahara; Hiroyasu Noma

Book ID
114394018
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
431 KB
Volume
39
Category
Article
ISSN
1368-8375

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Loss of heterozygosity on chromosome 2q:
Loss of heterozygosity on chromosome 2q: Possibly a poor prognostic factor in head and neck cancer
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Background. Loss of heterozygosity (LOH) correlates with inactivated tumor suppressor genes. The aim of this study was to see if LOH on chromosomes 2q, 3p, 5q, 9p, and 17p correlated with survival in early squamous cell carcinoma of the head and neck (SCCHN). Methods. A case control study was perfo

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Roentgenographically occult bronchogenic squamous cell carcinomas are early lung cancers that localize mainly within the bronchial wall and are thought to be a good model for elucidating chromosomal alterations during lung cancer progression. In this study, we analyzed allelic losses on chromosome r