Cells with abnormal TP53 lose cell cycle checkpoints, resulting in genomic instability and neoplastic transformation. However, the evidence linking the tumor-specific targets of genomic alteration to an abnormal TP53 is limited. The present study tested the hypothesis that TP53 abnormalities are cor
β¦ LIBER β¦
Allelic loss at the BRCA1, BRCA2 and TP53 loci in human sporadic breast carcinoma
β Scribed by A Katsama; G Sourvinos; G Zachos; D.A Spandidos
- Book ID
- 117469739
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 130 KB
- Volume
- 150
- Category
- Article
- ISSN
- 0304-3835
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Allelic loss at BRCA1, BRCA2, and adjace
β
Su-Ling Tseng; Jyh-Cherng Yu; Chung-Tai Yue; Shu-Fen Chang; Tzu-Ming Chang; Chen
π
Article
π
1997
π
John Wiley and Sons
π
English
β 60 KB
π 2 views
805 Alterations in BRCA1, BRCA2, TP53 an
β
J. Prokopcova; J. Soukupova; I. Ticha; M. Janatova; J. Sevcik; Z. Kleibl; P. Kle
π
Article
π
2010
π
Elsevier Science
π
English
β 47 KB
The role of alterations in BRCA1, BRCA2,
β
I. Ticha; J. Soukupova; M. Janatova; Z. Kleibl; P. Pohlreich
π
Article
π
2008
π
Elsevier Science
π
English
β 85 KB
179 Allelic loss on p16, BRCA1, BRCA2, P
β
C. Park; S. Choi; S. Cho
π
Article
π
2010
π
Elsevier Science
π
English
β 62 KB
288 POSTER Inactivation of the BRCA1-, B
π
Article
π
2005
π
Elsevier Science
π
English
β 143 KB
Sporadic breast cancer in young women: P
β
Suzanne M. Johnson; Jacqueline A. Shaw; Rosemary A. Walker
π
Article
π
2002
π
John Wiley and Sons
π
French
β 132 KB
## Abstract Previous studies have shown that breast cancers have more aggressive pathologic features in young women. In order to examine genetic alterations associated with earlyβonset breast cancer, 31 patients with no known family history, aged 26β35 years at diagnosis, were examined for loss of