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Allelic imbalance of the mutant and wild-type RET allele in MEN 2A-associated medullary thyroid carcinoma

✍ Scribed by Koch, Christian A; Huang, Steve C; Moley, Jeffrey F; Azumi, Norio; Chrousos, George P; Gagel, Robert F; Zhuang, Zhengping; Pacak, Karel; Vortmeyer, Alexander O


Book ID
110066220
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
123 KB
Volume
20
Category
Article
ISSN
0950-9232

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Communicated by Kenneth K. Kidd Gennline missense mutations within the coding region of the RET proto-oncogene have recently been described in patients with the dominantly inherited cancer syndromes, multiple endocrine neoplasia type 2a (MEN 2a) and familial medullary thyroid carcinoma (FMTC). To da