𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Allelic imbalance in three distinct regions on chromosome 17q in sporadic breast cancer correlates with prognostic parameters

✍ Scribed by U. Hamann; S.D. Costa; K. Götte; J. Huober; E.-F. Solomayer; M. Kaufmann; G. Bastertt; D. Komitowski

Book ID
114316966
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
968 KB
Volume
6
Category
Article
ISSN
0960-9776

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Identification of two distinct regions o
Identification of two distinct regions of allelic imbalance on chromosome 18q in metastatic prostate cancer
✍ Susan S. Padalecki; Dean A. Troyer; Marc F. Hansen; Tomo Saric; Barbara G. Schne 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 115 KB 👁 2 views

Like most cancers, prostate cancer (CaP) is believed to be the result of the accumulation of genetic alterations within cells. Previous studies have implicated numerous chromosomal regions with elevated rates of allelic imbalance (AI), using mostly primary CaPs with an unknown disease outcome. These

At least two different regions are invol
At least two different regions are involved in allelic imbalance on chromosome arm 16q in breast cancer
✍ Dr. Anne-Marie Cleton-Jansen; Elna W. Moerland; Net J. Kuipers-Dijkshoorn; Cees 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 565 KB

## Abstract Loss of heterozygosity (LOH) or allelic imbalance, the latter term referring to both loss and gain of an allele, on the long arm of chromosome 16 has been repeatedly found in cancers of, e.g., the breast and prostate. This indicates the presence of one or more tumor suppressor genes on

High frequency of allelic imbalance at c
High frequency of allelic imbalance at chromosome region 16q22-23 in human breast cancer: Correlation with high pgr and low s phase
✍ Sigurlaug Skirnisdottir; Gudny Eiriksdottir; Trausti Baldursson; Rosa B. Barkard 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 668 KB

The loss of genetic material from a specific chromosome region in tumors suggests the presence of tumor-suppressor genes. Loss of heterozygosity (LOH) or allelic imbalance (Al) on the long arm of chromosome 16 is a known event in sporadic breast cancer. To locate the commonly deleted regions, and th

Detailed deletion mapping in sporadic br
Detailed deletion mapping in sporadic breast cancer at chromosomal region 17p13 distal to the TP53 gene: association with clinicopathological parameters
✍ Susanne Seitz; Konstanze Poppe; Jörg Fischer; Anita Nothnagel; Lope Estévez-Schw 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB 👁 2 views

Chromosome 17p is among the most frequently deleted regions in a variety of human malignancies including breast cancer. This study has further refined the localization of a putative tumour suppressor gene (TSG) at 17p13 distal to the TP53 gene in breast carcinomas. It was found that 73% (37 of 51) o