## Abstract Retinoids play essential roles in the regulation of cell differentiation and in the proliferation of various epithelial tissues, and atRA is one such active metabolite of retinoids. However, despite the known functions of atRA, its clinical applications are limited due to the induced me
✦ LIBER ✦
All-trans-retinoic acid inhibits growth of head and neck cancer stem cells by suppression of Wnt/β-catenin pathway
✍ Scribed by Young Chang Lim; Hyun Jung Kang; Young Sook Kim; Eun Chang Choi
- Book ID
- 119233290
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 773 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0959-8049
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In order to better understand the mechanisms that underlie the antiproliferative effect of retinoids, we have examined the response of human carcinoma cell lines to all-trans retinoic acid (RA) and N-(4-hydroxyphenyl) retinamide (4HPR) in terms of cell growth, apoptosis and regulation of retinoic ac