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All-trans retinoic acid for the treatment of acute promyelocytic leukemia in pregnancy

โœ Scribed by Marc H. Incerpi; David A. Miller; Robert Posen; James D. Byrne

Book ID
117192700
Publisher
Lippincott Williams and Wilkins
Year
1997
Tongue
English
Weight
450 KB
Volume
89
Category
Article
ISSN
0029-7844

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Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,