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All-trans retinoic acid activates E-cadherin expression via promoter hypomethylation in the human colon carcinoma HCT116 cells

โœ Scribed by Young-Ju Woo; Kyung Lib Jang


Book ID
116303874
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
825 KB
Volume
425
Category
Article
ISSN
0006-291X

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Background and Objectives: Retinoids are metabolized in human intestinal epithelial cells to all-trans retinoic acid; however, it is unknown whether these cells express retinoid receptors, and whether sensitivity or resistance to the hormone is associated with a particular pattern of expression of r