Transcriptional repression of the human collagenase-1 (MMP-1) gene in MDA231 breast cancer cells by all-trans-retinoic acid requires distal regions of the promoter

Transcriptional regulation of the homeob

Transcriptional regulation of the homeobox gene NKX3.1 by all-trans retinoic acid in prostate cancer cells

✍ Marc A. Thomas; Myles C. Hodgson; Susan D. Loermans; Joel Hooper; Raelene Enders 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 283 KB 👁 2 views

## Abstract __NKX3.1__ is a homeobox gene, expression of which is largely restricted to the adult prostatic epithelium. Loss of NKX3.1 expression has been linked to prostate carcinogenesis and disease progression and occurs in the absence of mutations in the coding region of the __NKX3.1__ gene. In