๐”– Bobbio Scriptorium
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Alkylation of Sulfamic Esters with 4-Fluorobenzyl Bromide

โœ Scribed by Khaled Debbabi; Mohamed Beji; Ahmed Baklouti


Book ID
101978536
Publisher
John Wiley and Sons
Year
2005
Weight
19 KB
Volume
36
Category
Article
ISSN
0931-7597

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The O-silylated dienolates of unsaturated ketones and esters can be alkylated using zinc bromide catalysis to give predominantly the y-alkylated carbonyl compounds. The substitution pattern of the substrate (11, favours, in certain cases, very high or complete y-selectivity.

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