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Alkylation of DNA by the Nitrogen Mustard Bis-(2-chloroethyl)methylamine

✍ Scribed by Osborne, Martin R.; Wilman, Derry E. V.; Lawley, Philip D.

Book ID
126413927
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
578 KB
Volume
8
Category
Article
ISSN
0893-228X

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## Abstract The concentration of ^3^H‐aniline mustard in two tumour lines has been measured and the level of binding of the drug to DNA followed for 48 hours after intraperitoneal injection. Although the two tumour lines differ a hundred‐fold in their sensitivity to this alkylating agent, no good c