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Alkylation of allylic derivatives. 9. On the stereochemistry of alkylation of acyclic allylic alcohols by the Murahashi method

✍ Scribed by Goering, Harlan L.; Tseng, Chung Chyi


Book ID
126216578
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
368 KB
Volume
50
Category
Article
ISSN
0022-3263

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An attempted enantioselective synthesis of all the four individual diastereomers of a,b-dimethylated mycophenolic acid using Evans chiral auxiliaries is reported. The 1,3-allylic strain effect on the enolates used favor the formation of the syn acids.