Alkylation of Aldehydes with Trialkylboranes in Water

✍ Scribed by Koji Hirano; Hideki Yorimitsu; Koichiro Oshima

• Publisher: John Wiley and Sons
• Year: 2006
• Tongue: English
• Weight: 89 KB
• Volume: 348
• Category: Article
• ISSN: 1615-4150
• DOI: 10.1002/adsc.200606136

✦ Synopsis

Abstract

Water enables the alkylation of aldehydes with trialkylboranes under nickel catalysis without the addition of a base. Trialkylboranes prepared from borane‐dimethyl sulfide and terminal olefins via hydroboration as well as commercially available trialkylboranes could be employed for the reaction. The reaction would proceed via η^2^‐coordinated nickel complexes with aldehydes as the key intermediates.